The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2025
Filed:
May. 01, 2019
The Johns Hopkins University, Baltimore, MD (US);
Bailey Surtees, Edmond, OK (US);
Evelyn McChesney, Baltimore, MD (US);
Sean Young, Baltimore, MD (US);
Yixin Hu, Baltimore, MD (US);
Nicholas James Durr, Baltimore, MD (US);
Tara Blair, Baltimore, MD (US);
Pascal Acree, Baltimore, MD (US);
Grace Kuroki, Baltimore, MD (US);
Susan C. Harvey, Lutherville, MD (US);
Serena M. Thomas, Summit, NJ (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
An embodiment in accordance with the present invention provides a handheld cryoprobe for use in percutaneous cryotherapy of tumorous masses. It includes a probe attached to a COgas dispensing backend. The probe has specifically optimized parameters designed for use with COgas and is made out of a partially hollowed and threaded aluminum rod providing maximum heat exchange. The system backend regulates flow of compressed COgas while throttling and cooling the gas coolant to the cytotoxically low temperatures necessary for targeted tumor cell death. Additionally, the incoming initial stream of COgas is throttled by the Joule-Thomson nozzle on the backend. The low temperature exhaust gas is then used to pre-cool all subsequent incoming gas, resulting in an even lower temperature at the probe tip, which provides a positive feedback loop, continually decreasing the gas's temperature. The temperature drop is caused by the Joule-Thomson effect.