The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2025

Filed:

Dec. 09, 2021
Applicant:

The Chinese University of Hong Kong, Hong Kong, CN;

Inventors:

Renjie Zhou, Hong Kong, CN;

Xin Shu, Hong Kong, CN;

Rishikesh Pandey, Unionville, CT (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01); G06N 3/045 (2023.01); G06V 10/778 (2022.01); G06V 10/94 (2022.01); G06V 30/18 (2022.01); G06V 30/19 (2022.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); G06N 3/045 (2023.01); G06V 10/778 (2022.01); G06V 10/94 (2022.01); G06V 30/18057 (2022.01); G06V 30/1912 (2022.01); G06V 30/19127 (2022.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30024 (2013.01);
Abstract

The subject invention pertains to methods and systems for classifying leukocytes using artificial intelligence called AIRFIHA (artificial-intelligence enabled reagent-free imaging hematology analyzer) that can accurately classify subpopulations of leukocytes in a label-free manner. AIRFIHA can not only subtype lymphocytes into B and T cell but is capable of sorting different types of T cells subtypes. AIRFIHA is realized through training a two-step neural network using label-free images of separated leukocytes acquired from a custom-built quantitative phase microscope. Owing to its easy operation, low cost, and strong discerning capability of complex leukocyte subpopulations, AIRFIHA is clinically translatable and can also be deployed in resource-limited settings.


Find Patent Forward Citations

Loading…