The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2025
Filed:
Dec. 27, 2019
Applicant:
Galderma Holding SA, La Tour-De-Peilz, CH;
Inventors:
Assignee:
Galderma Holding SA, Zug, CH;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08J 3/075 (2006.01); C08J 3/24 (2006.01); C08K 5/1545 (2006.01);
U.S. Cl.
CPC ...
C08J 3/075 (2013.01); C08J 3/24 (2013.01); C08J 2305/02 (2013.01); C08J 2305/10 (2013.01); C08K 5/1545 (2013.01);
Abstract
A method of preparing a hydrogel product comprising crosslinked glycosaminoglycan molecules, comprising the steps of: (a) providing a mixed solution of glycosaminoglycan molecules, a di- or multinucleophilic functional crosslinker, and a mononucleophilic functional graft chain; (b) activating carboxyl groups on the glycosaminoglycan molecules with a coupling agent to form activated glycosaminoglycan molecules; and (c) simultaneously crosslinking the activated glycosaminoglycan molecules and grafting the graft chain to the activated glycosaminoglycan molecules by reacting the nucleophiles with the activated carboxyl groups.