The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2025

Filed:

Jan. 06, 2023
Applicant:

Northwestern University, Evanston, IL (US);

Inventors:

Hemant K. Roy, Chestnut Hill, MA (US);

Vadim Backman, Chicago, IL (US);

Assignee:

Northwestern University, Evanston, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 31/282 (2006.01); A61K 38/00 (2006.01); A61K 38/19 (2006.01); A61P 3/10 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 14/475 (2006.01); C07K 14/52 (2006.01);
U.S. Cl.
CPC ...
C07K 14/475 (2013.01); A61K 31/282 (2013.01); C07K 14/4703 (2013.01); A61K 38/00 (2013.01);
Abstract

Disclosed are compositions comprising myokines and their methods of preparation and use. The disclosed myokine compositions and methods may comprise myokines having a molecular weight of greater than about 10 kDa such as myostatin and metrnl. The disclosed myokine compositions and methods may be utilized for treating and/or preventing cell proliferative and metabolic diseases and disorders. In particular, the disclosed myokine compositions and methods may be utilized for treating and/or preventing cell proliferative and metabolic diseases and disorders, such as cancer, and metabolic diseases and disorders, such as diabetes, non-alcoholic fatty liver disease, and heart disease.


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