The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2025
Filed:
Jan. 14, 2019
Children's Medical Center Corporation, Boston, MA (US);
The Regents of the University of California, Oakland, CA (US);
Min Dong, Weatogue, CT (US);
Liang Tao, Boston, MA (US);
Rongsheng Jin, Irvine, CA (US);
Peng Chen, Oakland, CA (US);
Aina He, Boston, MA (US);
Children's Medical Center Corporation, Boston, MA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Provided herein are agents that bind to the lipid binding groove of Frizzled (FZD). In some embodiments, the agent is a fragment of TcdB corresponding to amino acids 1285-1804 of SEQ ID NO: 1. In some embodiments, binding of the agent to the lipid binding groove of FZD inhibits TcdB entry into cells, and/or inhibits Wnt signaling. Methods of treatinginfection (CDI) and methods of treating cancer are also provided.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile