The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2025

Filed:

Apr. 13, 2022
Applicant:

Sonivie Ltd., Rosh HaAyin, IL;

Inventors:

Or Shabtay, Kibbutz Farod, IL;

Dalit Shav, Glen Rock, NJ (US);

Assignee:

Sonivie Ltd., Rosh HaAyin, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 7/00 (2006.01); A61B 17/3203 (2006.01); A61B 18/00 (2006.01); A61B 18/02 (2006.01); A61B 18/06 (2006.01); A61B 18/08 (2006.01); A61B 18/14 (2006.01); A61B 18/24 (2006.01); A61K 31/191 (2006.01); A61K 31/343 (2006.01); A61K 31/4965 (2006.01); A61K 31/4985 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/53 (2006.01); A61N 2/02 (2006.01); A61N 2/06 (2006.01); A61N 5/10 (2006.01); A61N 7/02 (2006.01); A61B 5/055 (2006.01); A61B 6/03 (2006.01); A61B 6/50 (2024.01); A61B 17/00 (2006.01); A61B 18/12 (2006.01); A61B 18/18 (2006.01);
U.S. Cl.
CPC ...
A61N 7/00 (2013.01); A61B 18/00 (2013.01); A61B 18/0206 (2013.01); A61B 18/082 (2013.01); A61B 18/1492 (2013.01); A61B 18/24 (2013.01); A61K 31/191 (2013.01); A61K 31/343 (2013.01); A61K 31/4965 (2013.01); A61K 31/4985 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 31/53 (2013.01); A61N 2/06 (2013.01); A61N 5/1002 (2013.01); A61N 7/022 (2013.01); A61B 5/055 (2013.01); A61B 6/032 (2013.01); A61B 6/504 (2013.01); A61B 2017/00292 (2013.01); A61B 2018/00369 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/0212 (2013.01); A61B 2018/1253 (2013.01); A61B 2018/126 (2013.01); A61B 2018/1807 (2013.01); A61B 2018/1861 (2013.01); A61N 2007/003 (2013.01); A61N 2007/0043 (2013.01); A61N 2007/0078 (2013.01);
Abstract

Disclosed herein is a therapeutically active agent usable in the treatment of pulmonary arterial hypertension (PAH), for use in the treatment of pulmonary arterial hypertension, as well as methods of treating PAH, said treatment and methods comprising administering such an active agent and effecting pulmonary artery denervation in the subject. In some aspects, a sub-therapeutically effective amount of the active agent is administered. In some aspects, the method is devoid of administering such an active agent for at least one month subsequent to the denervation. Further disclosed is a method of treating PAH comprising determining a responsiveness of the subject to at least one therapeutically active agent usable in treating PAH; and effecting pulmonary artery denervation in a subject responsive to the active agent(s).


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