The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2025

Filed:

Jun. 06, 2019
Applicants:

The Research Foundation for the State University of New York, New York, NY (US);

Inspirx, Inc., Durham, NC (US);

Inventors:

Gerald Smaldone, Stony Brook, NY (US);

Rohinton Toddywala, Somerset, NY (US);

Akanksha Hande, Somerset, NY (US);

Vijay Shukla, Somerset, NY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 11/06 (2006.01); A61M 11/00 (2006.01); A61M 15/00 (2006.01); A61M 16/00 (2006.01); A61M 16/04 (2006.01); A61M 16/08 (2006.01); A61M 16/14 (2006.01); A61M 16/20 (2006.01);
U.S. Cl.
CPC ...
A61M 11/06 (2013.01); A61M 11/00 (2013.01); A61M 15/0095 (2014.02); A61M 16/0057 (2013.01); A61M 16/04 (2013.01); A61M 16/0883 (2014.02); A61M 2016/0027 (2013.01); A61M 16/0875 (2013.01); A61M 16/147 (2014.02); A61M 16/204 (2014.02); A61M 2205/3331 (2013.01); A61M 2206/20 (2013.01);
Abstract

A breath-enhanced nebulizer adapted for use in administering an aerosolized pharmaceutical composition to a patient by inhalation wherein the patient is connected to a mechanical ventilator is disclosed. The nebulizer has a Venturi driven by a nebulizer air supply that draws a solution of a pharmaceutical composition into a shear zone where the solution is atomized. The Venturi effect is amplified by the internal configuration of the nebulizer to increase the rate of nebulization of drug. Optionally, breath-actuated nebulization is used, employing a pressure sensor interposed between the nebulizer and mechanical ventilator that controls the nebulizer air supply, such that nebulizer air and concomitant nebulization only occurs during the inhalation phase of a breathing cycle.


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