The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2025
Filed:
Nov. 08, 2019
Applicant:
Arbutus Biopharma Corporation, Burnaby, CA;
Inventors:
James Heyes, Vancouver, CA;
Adam Judge, Bainbridge Island, WA (US);
Kieu Mong Lam, Richmond, CA;
Lorne Ralph Palmer, Vancouver, CA;
Petra Schreiner, Burnaby, CA;
Assignee:
ARBUTUS BIOPHARMA CORPORATION, Burnaby, CA;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/1272 (2025.01); A61K 9/51 (2006.01); A61K 31/713 (2006.01); B82Y 5/00 (2011.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/1272 (2013.01); A61K 9/5123 (2013.01); A61K 31/713 (2013.01); C12N 15/113 (2013.01); B82Y 5/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01);
Abstract
The invention provides certain specific lipid nanoparticles comprising: (a) one or more nucleic acid molecules; (b) cholesterol; (c) DSPC; (d) PEG-C-DMA; and (e) a cationic lipid; and pharmaceutical compositions comprising the lipid nanoparticles. The lipid nanoparticles and pharmaceutical compositions are particularly useful for delivering a nucleic acid such as siRNA or mRNA to a patient (e.g. a human) or to a cell.