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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12251425 B1

PDFFull Text
Date of Patent:
Mar. 18, 2025

Filed:

Feb. 17, 2020

Sustained-release lipid preformulation and pharmaceutical composition for sustained-release injection in form of lipid solution containing same

Applicant:

Imdpharm Inc., Suwon-si, KR;

Inventors:

Young-Joon Park, Seoul, KR;

Sang-Won Jeon, Suwon-si, KR;

Sook Choi, Seoul, KR;

Assignee:

IMDPHARM INC., Suwon-si, KR;

Attorneys:

Vorys, Sater, Seymour and Pease LLP

Mih Suhn Koh

Primary Examiner:

Katherine Peebles

Assistant Examiner:

Afua Bamfoaa Boateng

Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/445 (2006.01); A61K 31/519 (2006.01); A61K 31/522 (2006.01); A61K 38/09 (2006.01); A61K 38/26 (2006.01); A61K 38/31 (2006.01); A61K 47/12 (2006.01); A61K 47/14 (2017.01); A61K 47/22 (2006.01); A61K 47/24 (2006.01);
U.S. Cl.
CPC ...
A61K 38/31 (2013.01); A61K 9/0019 (2013.01); A61K 31/445 (2013.01); A61K 31/519 (2013.01); A61K 31/522 (2013.01); A61K 38/09 (2013.01); A61K 38/26 (2013.01); A61K 47/12 (2013.01); A61K 47/14 (2013.01); A61K 47/22 (2013.01); A61K 47/24 (2013.01);
Abstract

Provided is a sustained-release lipid pre-concentrate in the form of a lipid solution, including an unsaturated fatty acid having 14 to 20 carbon atoms (C14˜C20); a phospholipid; and α-tocopherol acetate, wherein the sustained-release lipid pre-concentrate is free of diacyl glycerol and sorbitan unsaturated fatty acid ester; and forms a liquid crystal in an aqueous medium. Further provided is a sustained-release injectable pharmaceutical composition in the form of a lipid solution, including the pre-concentrate and a pharmacologically active substance, wherein the sustained-release injectable pharmaceutical composition is free of diacyl glycerol and sorbitan unsaturated fatty acid ester.

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