The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2025
Filed:
Jun. 05, 2024
Applicant:
Remedy Pharmaceuticals, Inc., New York, NY (US);
Inventors:
Sven Martin Jacobson, New York, NY (US);
Thomas W. Macallister, Montross, VA (US);
Assignee:
REMEDY PHARMACEUTICALS, INC., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/64 (2006.01); A61B 17/22 (2006.01); A61P 9/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/64 (2013.01); A61B 17/22 (2013.01); A61P 9/10 (2018.01); A61B 2017/22082 (2013.01);
Abstract
The invention relates to the treatment of ischemic stroke at risk of brain swelling using SUR1-TRPM4 channel inhibitors in combination with mechanical thrombectomy. In some embodiments, the methods include treating patients suffering from a large hemispheric infarction. In certain embodiments, patients have a lesion volume of less than 140 cmor less than 125 cmas measured by MRI DWI or CTP. The patient may have suffered a wake-up stroke. Some embodiments involve treating patients who also undergo decompressive therapy.