The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2025
Filed:
Feb. 05, 2019
Applicants:
The Regents of the University of California, Oakland, CA (US);
Chiba University, Chiba, JP;
Inventors:
Bruce D. Hammock, Davis, CA (US);
Sung Hee Hwang, Woodland, CA (US);
Kenji Hashimoto, Chiba, JP;
Qian Ren, Chiba, JP;
Assignees:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
CHIBA UNIVERSITY, Chiba, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/453 (2006.01); A61K 31/198 (2006.01); A61K 31/415 (2006.01); A61K 31/4525 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61P 25/28 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/453 (2013.01); A61K 31/198 (2013.01); A61K 31/415 (2013.01); A61K 31/4525 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01);
Abstract
Provided are methods of preventing, delaying, mitigating, reducing and/or inhibiting alpha-synuclein aggregates in the brains of a subject at risk of developing or suffering a cognitive disease associated with, caused and/or mediated at least in part by alpha-synuclein aggregates, for example, Parkinson's Disease or Dementia with Lewy Bodies (DLB).