The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 2025

Filed:

Nov. 28, 2018
Applicant:

Fons Jk Group, A.s., Pardubice, CZ;

Inventors:

Michal Holcapek, Stare Hradiste, CZ;

Eva Cifkova, Krhova, CZ;

Miroslav Lisa, Bezdekov, CZ;

Robert Jirasko, Pardubice, CZ;

Denise Wolrab, Vienna, AT;

Tereza Hrnciarova, Prague, CZ;

Assignee:

FONS JK Group, a.s., Pardubice, CZ;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 30/72 (2006.01); G01N 33/92 (2006.01); G01N 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57488 (2013.01); G01N 33/92 (2013.01); G01N 2405/02 (2013.01); G01N 2405/04 (2013.01); G01N 2405/08 (2013.01);
Abstract

A method of diagnosing cancer based on lipidomic analysis of a body fluid taken from the body of a patient is disclosed. The method includes the steps of spiking of the sample with a set of internal standards having at least one internal standard for each lipid class present in the sample, subsequently processing the sample by liquid-liquid lipidomic extraction or by solid phase lipidomic extraction, measurement of the processed sample by a mass spectrometry method, determining concentrations for at least 51, more preferably for all lipids present at a level above detection threshold of the mass spectrometry method, statistical evaluation of the determined concentrations of the lipids, the statistical evaluation determining the level of probability of the patient suffering from cancer, or optionally from a specific type of cancer.


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