The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 2025

Filed:

Apr. 26, 2021
Applicant:

The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);

Inventors:

Jonathan R. Coppeta, Windham, NH (US);

Joseph L Charest, Cambridge, MA (US);

Else M. Vedula, Brookline, MA (US);

Jeffrey T. Borenstein, Newton, MA (US);

Abigail June Spencer, Boston, MA (US);

Brett C. Isenberg, West Newton, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/12 (2006.01); C12M 1/00 (2006.01); C12M 1/32 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01); C12M 1/42 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01); C12N 5/071 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12M 25/04 (2013.01); C12M 21/08 (2013.01); C12M 23/12 (2013.01); C12M 23/16 (2013.01); C12M 25/02 (2013.01); C12M 29/00 (2013.01); C12M 35/08 (2013.01); C12M 41/00 (2013.01); C12M 41/48 (2013.01); C12N 5/0686 (2013.01); C12N 5/069 (2013.01); G01N 33/5082 (2013.01); C12N 2533/30 (2013.01); C12N 2535/00 (2013.01);
Abstract

The methods and systems described herein provide a cell culture platform with an array of tissue modeling environments and dynamic control of fluid flow. The cell culture platform includes an array of wells that are fluidically coupled by microchannel structures. The dynamically controlled flow of fluid interacts with cells grown within the microchannels.


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