The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2025
Filed:
Dec. 26, 2019
Imcheck Therapeutics Sas, Marseilles, FR;
Institut Jean Paoli & Irene Calmettes, Marseilles, FR;
Centre National DE LA Recherche Scientifique—cnrs, Paris, FR;
Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;
Université D'aix-marseille, Marseilles, FR;
Alemseged Truneh, Sudbury, MA (US);
Christine Pasero, Marseilles, FR;
René Hoet, Marseilles, FR;
Magali Colazet, Marseilles, FR;
Daniel Olive, Marseilles, FR;
IMCHECK THERAPEUTICS SAS, Marseilles, FR;
INSTITUT JEAN PAOLI & IRENE CALMETTES, Marseilles, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, Paris, FR;
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), Paris, FR;
UNIVERSITE D'AIX-MARSEILLE, Marseilles, FR;
Abstract
It is disclosed anti-BTN3A activating antibody fragments that specifically bind to BTN3A and activate the cytolytic function of Vγ9/Vδ2 T cells. The disclosure more specifically relates to specific anti-BTN3A binding proteins comprising such activating antibody fragments and their use in the manufacturing of novel drugs for use in treating cancer disorders, in particular cancers susceptible to be treated with activated γδ T cells.