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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12247062 B1

PDFFull Text
Date of Patent:
Mar. 11, 2025

Filed:

Dec. 08, 2015

Soluble universal adcc-enhancing synthetic fusion gene and peptide technology and its use thereof

Applicant:

1globe Biomedical Co., Ltd., Beijing, CN;

Inventors:

Chiang J. Li, Cambridge, MA (US);

Shyam Unniraman, Newton, MA (US);

Assignee:

1GLOBE BIOMEDICAL CO., LTD., Beijing, CN;

Attorneys:

Milstein Zhang & Wu LLC

Duan Wu, Esq.

Primary Examiner:

Michael Allen

Int. Cl.
CPC ...
C07K 14/735 (2006.01); C07K 16/28 (2006.01); C07K 16/46 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70535 (2013.01); C07K 16/2806 (2013.01); C07K 16/2809 (2013.01); C07K 16/46 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); C07K 2319/74 (2013.01);
Abstract

Novel synthetic biology-based ADCC technologies are provided that enhance or enable ADCC responses, for example, through a rationally-designed soluble universal ADCC enhancer protein (SUAEP) where a high-affinity CD3-binding domain is fused to a high-affinity Fc-binding domain. The SUAEP technology can be used to prevent or treat cancers, infectious, inflammatory or autoimmune diseases, and other diseases where elimination of diseased cells is desirable.

Find Patent Forward Citations

Li, Chiang. (2025). Soluble universal adcc-enhancing synthetic fusion gene and peptide technology and its use thereof (U.S. Patent No. 12247062). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12247062

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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