The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 2025

Filed:

Dec. 08, 2022
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Mark Edward Zak, Davidsonville, MD (US);

Naomi S. Rajapaksa, San Mateo, CA (US);

Yun-Xing Cheng, Beijing, CN;

Jessica Grandner, San Mateo, CA (US);

Daniel G. M. Shore, Redwood City, CA (US);

F. Anthony Romero, Redwood City, CA (US);

Marian C. Bryan, Fort Washington, PA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 37/06 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 37/06 (2018.01);
Abstract

Compounds of formula (I) wherein R, R, R, R, Rand Rare as defined herein, and salts thereof, that are useful as JAK kinase inhibitors are described herein. Also provided are pharmaceutical compositions that include such a JAK inhibitor and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient.


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