The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2025
Filed:
Dec. 06, 2019
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Ashok Arasappan, Bridgewater, NJ (US);
Jason M. Cox, Flemington, NJ (US);
John S. Debenham, Scotch Plains, NJ (US);
Zhuyan Guo, Scotch Plains, NJ (US);
Zhong Lai, East Brunswick, NJ (US);
Dongfang Meng, Morganville, NJ (US);
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
The present invention is directed to cyclobutyl pyrazolopyrimidine compounds which may be useful as therapeutic agents for the treatment of disorders associated with phosphodiesterase 9 (PDE9). The present invention also relates to the use of such compounds for treating cardiovascular and cerebrovascular diseases, such as hypertension, chronic kidney disease and heart failure, and neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.