Wound dressing based on polymeric mixture of cellulose acetate and hyaluronic acid embedded with copper oxide and magnesium oxide nanoparticles

Abstract

Wound dressings fabricated from a polymeric mixture of cellulose acetate and hyaluronic acid embedded with copper oxide and/or magnesium oxide nanoparticles and a method of making the wound dressing. The method includes combining hyaluronic acid and deionized water to form a first mixture, combining cellulose acetate and acetone to form a second mixture, combining the first and second mixtures to form a third mixture of hyaluronic acid, cellulose acetate, deionized water and acetone, separately adding at least one of a copper acetate solution and a magnesium chloride solution to the third mixture to form a fourth mixture, adding sodium hydride to the fourth mixture to form a final mixture, and drying the final mixture to form a film used for the wound dressing. Different weights of copper oxide and magnesium oxide can be chosen to achieve a certain morphological appearance. The wound dressing is a promising option for wound healing.