The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2025
Filed:
Mar. 27, 2023
Ascendis Pharma A/s, Hellerup, DK;
Sebastian Stark, Heidelberg, DE;
Thomas Knappe, Heidelberg, DE;
Harald Rau, Heidelberg, DE;
Nicola Bisek, Heidelberg, DE;
Burkhardt Laufer, Heidelberg, DE;
Samuel Weisbrod, Heidelberg, DE;
Tobias Voigt, Heidelberg, DE;
Ascendis Pharma A/S, Hellerup, DK;
Abstract
The present invention relates to hydrogel prodrug compositions comprising cross-linked hyaluronic acid (HA), or a derivative or a salt thereof, wherein the cross-linker system comprises a biodegradable spacer, wherein the cross-linked HA comprises a conjugated drug-linker, and wherein the linker is capable of releasing the drug under physiological conditions. The present invention further relates to methods for preparing the hydrogel prodrug compositions. The present invention further relates to methods for treating an ocular condition using the hydrogel compositions.