The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2025
Filed:
Jul. 15, 2019
Universitat Autònoma DE Barcelona, Barcelona, ES;
Consorcio Centro DE Investigación Biomédica En Red, M.p., Madrid, ES;
Fundació Institut DE Recerca DE L'hospital DE LA Santa Creu I Sant Pau, Barcelona, ES;
Jordi Surrallés Calonge, Barcelona, ES;
Jordi Minguillón Pedreño, Barcelona, ES;
Helena Montanuy Escribano, Barcelona, ES;
UNIVERSITAT AUTÒNOMA DE BARCELONA, Bellaterra, ES;
CONSORCIO CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED, M.P, Bellaterra, ES;
FUNDACIÓ INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU, Barcelona, ES;
Abstract
The present invention provides the afatinib or a pharmaceutically salt thereof for use in the treatment and/or prevention of a cancer in a patient suffering from a disease caused by a defect in DNA damage repair mechanism. Surprisingly, when afatinib was administered to FA cells, it was confirmed that there was a therapeutic anti-cancer effect without any toxic side-effect on DNA.