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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12245740 B1

PDFFull Text
Date of Patent:
Mar. 11, 2025

Filed:

Oct. 10, 2022

Systems and methods to repair tissue defects

Applicant:

Scripps Health, San Diego, CA (US);

Inventors:

Darryl D. D'Lima, San Diego, CA (US);

Clifford W. Colwell, Jr., La Jolla, CA (US);

Assignee:

SCRIPPS HEALTH, San Diego, CA (US);

Attorney:

WILSON SONSINI GOODRICH & ROSATI

Primary Examiner:

Ernst V Arnold

Int. Cl.
CPC ...
A61L 27/20 (2006.01); A61B 1/00 (2006.01); A61B 34/30 (2016.01); A61B 90/00 (2016.01); A61F 2/08 (2006.01); A61F 2/30 (2006.01); A61L 27/02 (2006.01); A61L 27/24 (2006.01); A61L 27/36 (2006.01); A61M 5/142 (2006.01); A61M 5/20 (2006.01); B29C 64/112 (2017.01); B33Y 10/00 (2015.01); B33Y 70/00 (2020.01); C12N 5/077 (2010.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61B 1/00009 (2013.01); A61B 1/00 (2013.01); A61B 34/30 (2016.02); A61B 90/00 (2016.02); A61F 2/0805 (2013.01); A61F 2/0811 (2013.01); A61F 2/30756 (2013.01); A61F 2/3094 (2013.01); A61L 27/025 (2013.01); A61L 27/20 (2013.01); A61L 27/24 (2013.01); A61L 27/3604 (2013.01); A61L 27/3608 (2013.01); A61L 27/3612 (2013.01); A61M 5/14212 (2013.01); A61M 5/20 (2013.01); B29C 64/112 (2017.08); B33Y 10/00 (2014.12); B33Y 70/00 (2014.12); C12N 5/0654 (2013.01); C12N 5/0655 (2013.01); A61B 2017/00969 (2013.01); A61B 2090/395 (2016.02); A61F 2002/30962 (2013.01); A61L 2430/06 (2013.01);
Abstract

Methods of bioprinting a bio-ink construct on an internal tissue defect or a chondral defect during a minimally invasive surgery on an individual in need thereof are provided, comprising: visualizing the defect; positioning a bioprinter comprising a printhead within proximity of or in contact with the defect; and ejecting a bio-ink from the printhead onto the defect to form a bio-ink layer, thereby generating a bio-ink construct. Further provided are systems for bioprinting a bio-ink construct on an internal tissue defect during a minimally invasive surgery on an individual in need thereof, comprising a control system, an endoscope, and a bioprinter comprising a printhead.

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