The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

Jul. 11, 2022
Applicant:

Shanghai Polaris Biology Co., Ltd., Shanghai, CN;

Inventors:

Yupeng Cheng, Shanghai, CN;

Shuangwu Sun, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/40 (2006.01); H01J 49/00 (2006.01); H01J 49/02 (2006.01); H01J 49/04 (2006.01); H01J 49/10 (2006.01);
U.S. Cl.
CPC ...
H01J 49/40 (2013.01); H01J 49/0031 (2013.01); H01J 49/025 (2013.01); H01J 49/0495 (2013.01); H01J 49/105 (2013.01);
Abstract

Systems and methods are provided for the analysis of single particles with inductively coupled plasma-time of flight mass spectrometry. An ion compression device is operated in combination with an image current detector to improve a duty cycle of particle analysis. The image current detection device is used to determine a start time and an end time of a separate ion cloud which is derived from a single particle. The ion compression device stores and compresses each ion cloud based on instructions from the image current detector. The duty cycle of the particle analysis can be improved up to nearly 100%. The ion compression device is additionally operated with an ion filtration device to achieve a lower detection limit and a higher signal-to-noise ratio.


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