The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Dec. 22, 2020
10x Genomics, Inc., Pleasanton, CA (US);
Joshua Delaney, Oakland, CA (US);
Shalini Gohil, Castro Valley, CA (US);
Jill Herschleb, San Francisco, CA (US);
Adam Lowe, Mountain House, CA (US);
Albert Kim, Los Angeles, CA (US);
Meiliana Tjandra, Dublin, CA (US);
10x Genomics, Inc., Pleasanton, CA (US);
Abstract
The present disclosure provides compositions and methods for using fixed biological samples in partition-based assays. In at least one embodiment, the disclosure provides a composition comprising a fixed biological sample and an un-fixing agent contained in a partition, such as a discrete droplet. In some embodiments, the disclosure provides un-fixing agent compounds capable of catalytically cleaving crosslinks in fixed biological samples, particularly crosslinked nucleic acids, such as RNA.