The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Jan. 21, 2019
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Roland D. Kersten, Arlington, MA (US);
Jing-Ke Weng, Belmont, MA (US);
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Abstract
Lyciumin cyclic peptides and methods of producing lyciumin cyclic peptides are described. A host cell can include a transgene encoding a lyciumin precursor peptide, or a biologically-active fragment thereof. The lyciumin precursor peptide, or biologically-active fragment thereof, can include one or more core lyciumin peptide domains. The transgene can be expressed in the host cell to thereby produce a lyciumin precursor peptide, or biologically-active fragment thereof. The lyciumin precursor peptide, or biologically-active fragment thereof, can be converted to one or more lyciumin cyclic peptides in the host cell. A library of nucleic acids encoding lyciumin precursor peptides, or biologically-active fragments thereof, can be generated.