The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

Nov. 14, 2019
Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Maria Amann, Schlieren, CH;

Peter Bruenker, Schlieren, CH;

Christina Claus, Schlieren, CH;

Claudia Ferrara Koller, Schlieren, CH;

Sandra Grau-Richards, Schlieren, CH;

Ralf Hosse, Schlieren, CH;

Christian Klein, Schlieren, CH;

Viktor Levitski, Schlieren, CH;

Pablo Umana, Schlieren, CH;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); C07K 16/30 (2013.01); C07K 16/3053 (2013.01); C07K 16/40 (2013.01); C12Y 304/14005 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The invention relates to novel bispecific antigen binding molecules, comprising (a) at least one moiety capable of specific binding to a target cell antigen, (b) at least one moiety capable of specific binding to a costimulatory TNF receptor family member, and (c) a Fc domain composed of a first and a second subunit capable of stable association, and to methods of producing these molecules and to methods of using the same.


Find Patent Forward Citations

Loading…