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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12240893 B1

PDFFull Text
Date of Patent:
Mar. 04, 2025

Filed:

Oct. 30, 2019

Subcutaneous dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh)

Applicant:

Alexion Pharmaceuticals, Inc., Boston, MA (US);

Inventors:

Lori Volles, New Haven, CT (US);

Rajendra Pradhan, New Haven, CT (US);

Douglas L. Sheridan, Branford, CT (US);

Marc Vallee, Lexington, MA (US);

Xiang Gao, Guilford, CT (US);

Assignee:

Alexion Pharmaceuticals, Inc., Boston, MA (US);

Attorneys:

Nelson Mullins Riley & Scarborough LLP

Jane E. Remillard, Esq.

Jill Gorny Sloper, Esq.

Primary Examiner:

Laura B Goddard

Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61P 7/00 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61P 7/00 (2018.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

Provided are methods for clinical treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) comprising administering to the patient an anti-C5 antibody, or antigen binding fragment thereof, wherein the anti-C5 antibody, or antigen binding fragment thereof, is administered (or is for administration) subcutaneously according to a particular clinical dosage regimen (i.e., at a particular dose amount and according to a specific dosing schedule). In one embodiment, the patient has previously been treated with eculizumab (Soliris®).

Find Patent Forward Citations

Volles, Lori. (2025). Subcutaneous dosage and administration of anti-c5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (pnh) (U.S. Patent No. 12240893). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12240893

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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