The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Dec. 07, 2020
Ajou University Industry-academic Cooperation Foundation, Suwon-si, KR;
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Suwon-si, KR;
Abstract
A composition including a substance that inhibits an expression or activity of c-src and its use in inhibiting aggregation and/or migration of α-syn are disclosed. The composition may be a pharmaceutical composition and can be used for preventing or treating synucleinopathy. The substance can inhibit the signal transduction induced by α-syn migrating to adjacent cells, thus mitigating the cytotoxic influence of α-syn on the adjacent cells; and can inhibit the denaturation of monomeric α-syn into aggregated α-syn, which may be a major cause of synucleinopathy, and thus, can be beneficially used as a therapeutic agent for synucleinopathy.