The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

May. 30, 2024
Applicant:

Qilu Pharmaceutical Co., Ltd., Shandong, CN;

Inventors:

Yue Yu, Shandong, CN;

Guijiang Wang, Shandong, CN;

Jiulin Wang, Shandong, CN;

Zhenming An, Shandong, CN;

Qingmin Wang, Shandong, CN;

Daoyuan Li, Shandong, CN;

Chuanlei Liu, Shandong, CN;

Feifei Liu, Shandong, CN;

Huanlan Zheng, Shandong, CN;

Peng Wan, Shandong, CN;

Bo Xie, Shandong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/71 (2006.01); C12Q 1/37 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); C12Q 1/37 (2013.01); G01N 33/6848 (2013.01); C07K 2319/30 (2013.01); G01N 2333/71 (2013.01); G01N 2333/976 (2013.01);
Abstract

Provided is a composition comprising aflibercept and a variant thereof, wherein the variant is a truncation variant with a truncated VEGF binding portion of aflibercept, and wherein the content of the truncation variant is less than or equal to about 20% by mass percentage. Also provided is a pharmaceutical formulation comprising the composition. Further, provided are a method for detecting the variant and use of the variant in quality inspection or quality control of an aflibercept-containing product.


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