The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Mar. 07, 2022
Applicant:
Acceleron Pharma Inc., Cambridge, MA (US);
Inventors:
Ravindra Kumar, Cambridge, MA (US);
Asya Grinberg, Cambridge, MA (US);
Erik M. Vogan, Cambridge, MA (US);
Assignee:
Acceleron Pharma Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/71 (2006.01); A61K 38/00 (2006.01); A61P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); A61P 21/00 (2018.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of red blood cells or a tissue, such as bone, cartilage, muscle, fat, and/or neuronal tissue. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.