The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Mar. 16, 2020
Nissan Chemical Corporation, Tokyo, JP;
Peptidream Inc., Kawasaki, JP;
Hisayuki Takeuchi, Funabashi, JP;
Yukio Asaka, Funabashi, JP;
Akihiro Nagaya, Funabashi, JP;
Michiharu Handa, Funabashi, JP;
Keiichi Masuya, Kawasaki, JP;
Tomonori Taguri, Kawasaki, JP;
Yoshitaka Nemoto, Kawasaki, JP;
Yutaka Kobayashi, Kawasaki, JP;
Ayumu Matsuda, Kawasaki, JP;
Haruaki Kurasaki, Kawasaki, JP;
Douglas Robert Cary, Kawasaki, JP;
Nissan Chemical Corporation, Tokyo, JP;
PeptiDream Inc., Kawasaki, JP;
Abstract
The present invention is to provide a method for producing a peptide containing an N-alkylamino acid, which comprises the following Steps (1) to (3). Step (1): a step of mixing an N-terminal protected amino acid or an N-terminal protected peptide with a carboxylic acid halide or a halogenated alkyl formate; Step (2): a step of mixing an amino acid or a peptide in which the N-terminal and the C-terminal are not protected with a trialkylsilylating agent; and Step (3): a step of mixing the product obtained in Step (1) with the product obtained in Step (2).