The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

Dec. 27, 2019
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Timothy Bugni, Madison, WI (US);

Fan Zhang, Madison, WI (US);

Douglas R. Braun, Mount Horeb, WI (US);

David Andes, Verona, WI (US);

Miao Zhao, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/16 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 491/16 (2013.01); A61K 45/06 (2013.01);
Abstract

Turbinmicin, an isolated compound of Formula (I) or IA is provided. Turbinomycin compounds of Formula (II) or (IIA) are also provided. A compound isolated from a bacterial species from the sea squirt,, and having a chemical formula of CHNOis also provided. Compositions including turbinmicin and turbinmicin compounds, such as pharmaceutical compositions including effective amounts of turbinmicin or turbinomicing compounds for treating fungal infections such asand, including drug-resistant strains thereof, are also disclosed. Methods of treating fungal infections with turbinmicin, turbinmicin compounds and compositions thereof are disclosed.


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