The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

Jan. 20, 2020
Applicant:

Voronoi, Inc., Incheon, KR;

Inventors:

Myungho Jung, Hwaseong-si, KR;

Jungyeon Yun, Goyang-si, KR;

Dahoon Ma, Incheon, KR;

Sohyun Chung, Incheon, KR;

Hyeonho Jeon, Incheon, KR;

Heesun Ryu, Incheon, KR;

Hyunkyung Kim, Incheon, KR;

Hwan Kim, Seoul, KR;

Jungbeom Son, Incheon, KR;

Namdoo Kim, Incheon, KR;

Jieun Choi, Seoul, KR;

Daekwon Kim, Daegu, KR;

Assignee:

Voronoi, Inc., Incheon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 519/00 (2006.01); C07F 9/6561 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 519/00 (2013.01); C07F 9/6561 (2013.01);
Abstract

[Summary] The present invention relates to a pyrrolopyridine derivative and a pharmaceutical composition comprising the same as an active ingredient for prevention or treatment of a protein kinase-related disease. The pyrrolopyridine derivative has excellent inhibitory activity against various protein kinases including LRRK2, DYRK1, and CLK1 and exhibits an excellent suppressive effect on the growth of triple-negative breast cancer cells. A pharmaceutical composition comprising the same as an active ingredient can be advantageously used for treating or preventing protein kinase-related diseases, inter alia, cancers, degenerative brain diseases, and inflammatory diseases, and specifically for treating triple-negative breast cancer.


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