The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
May. 27, 2022
Applicant:
Edgewise Therapeutics, Inc., Boulder, CO (US);
Inventors:
Kevin Hunt, Boulder, CO (US);
Kevin Koch, Boulder, CO (US);
Alan Russell, Boulder, CO (US);
Stephen Schlachter, Boulder, CO (US);
Paul Winship, Cambridge, GB;
Grace Uzoho, Cambridge, GB;
Chris Steele, Cambridge, GB;
Assignee:
EDGEWISE THERAPEUTICS, INC., Boulder, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61P 21/00 (2006.01); C07D 237/04 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 405/10 (2006.01); C07D 405/14 (2006.01); C07D 417/10 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61P 21/00 (2018.01); C07D 237/04 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 405/10 (2013.01); C07D 405/14 (2013.01); C07D 417/10 (2013.01);
Abstract
Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-α.