The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Nov. 13, 2019
Sindy K. Y. Tang, Palo Alto, CA (US);
Kari C. Nadeau, Los Altos Hills, CA (US);
Bryan J. Bunning, San Mateo, CA (US);
Nicolas Castano, Stanford, CA (US);
Fengjiao Lyu, Stanford, CA (US);
Seth Cordts, Palo Alto, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Sindy K. Y. Tang, Palo Alto, CA (US);
Kari C. Nadeau, Los Altos Hills, CA (US);
Bryan J. Bunning, San Mateo, CA (US);
Nicolas Castano, Stanford, CA (US);
Fengjiao Lyu, Stanford, CA (US);
Seth Cordts, Palo Alto, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Abstract
Devices, methods, and kits are provided for allergy testing based on basophil activation in a blood sample. Susceptibility of an individual to an allergic reaction to an allergen is detected by collecting a blood sample from the individual and assaying for activation of basophils in response to stimulation with an allergen. In particular, a microfluidic device is provided for automating the assay for detecting basophil activation as an indication of the susceptibility of an individual to an allergic reaction as well as kits containing such a device and diagnostic methods for using such a device for allergy testing. Additionally, such a microfluidic device can be adapted for multiplexed detection of allergic responses to multiple allergens by performing assays in parallel to detect the basophil responses to each allergen.