The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

Apr. 09, 2020
Applicant:

Nitto Denko Avecia Inc., Milford, MA (US);

Inventor:

Karsten Keller, Mendon, MA (US);

Assignee:

Nitto Denko Avecia, Inc., Milford, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 19/00 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
B01J 19/0046 (2013.01); C07H 21/00 (2013.01); B01J 2219/00328 (2013.01); B01J 2219/00452 (2013.01); B01J 2219/00585 (2013.01); B01J 2219/0059 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00725 (2013.01);
Abstract

A method and apparatus for nucleic acid synthesis. The method employs a device including at least one deprotection unit to carry out a step of deprotection, at least one coupling unit to carry out a step of coupling, at least one oxidation/thiolation unit to carry out a step of oxidation or thiolation, at least one capping unit to carry out a step of capping, and at least one washing unit to carry out a step of washing. A plurality of reaction vessels for nucleic acid synthesis are moved to the units in accord with a synthesis scheme for a desired nucleic acid sequence and at least two reaction vessels are simultaneously acted upon at several of the units in series.


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