The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Feb. 01, 2022
Virginia Commonwealth University, Richmond, VA (US);
Richard T. Marconi, Midlothian, VA (US);
Jason A. Carlyon, Richmond, VA (US);
Virginia Commonwealth University, Richmond, VA (US);
Abstract
Provided herein are chimeric recombinant polypeptides (chimeritopes) for use in vaccines against Anaplasmosis, in assays for diagnosing Anaplasmosis and in assays for measuring antibody titers induced by vaccination. The chimeritopes comprise, for example, antigenic segments of threeproteins (OmpA, AipA and Asp14) and a non-antigenic segment of aOsp protein (e.g. OspC) that is 10 amino acids in length, proline rich and random coil in conformation. Compositions comprising the chimeritopes, optionally in combination with additionalproteins of interest, are also provided, as are methods of using the compositions as vaccines and diagnostic tools.