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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12239688 B1

PDFFull Text
Date of Patent:
Mar. 04, 2025

Filed:

Mar. 22, 2021

Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof

Applicant:

Xencor, Inc., Monrovia, CA (US);

Inventors:

Matthew Bernett, Monrovia, CA (US);

John Desjarlais, Pasadena, CA (US);

Rumana Rashid, Temple City, CA (US);

Rajat Varma, Monrovia, CA (US);

Christine Bonzon, Los Angeles, CA (US);

Assignee:

Xencor, Inc., Pasadena, CA (US);

Attorneys:

Kelly A. Plummer

Christopher J. Betti

Morgan, Lewis & Bockius, LLP

Primary Examiner:

Vanessa L Ford

Assistant Examiner:

Sandra undefined Carter

Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 38/17 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2086 (2013.01); A61K 38/1793 (2013.01); A61K 39/3955 (2013.01); A61P 35/00 (2018.01); C07K 14/5443 (2013.01); C07K 14/7155 (2013.01); C07K 16/2818 (2013.01); C07K 16/28 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention is directed to novel IL-15/IL-15Rα heterodimeric Fc fusion proteins and uses thereof. The IL-15/IL-15Rα heterodimeric Fc fusion proteins can be administered to a patient to treat cancer. In some cases, the IL-15/IL-15Rα heterodimeric Fc fusion protein is administered in combination with a checkpoint blockage antibody such as a PD-1 antibody.

Find Patent Forward Citations

Bernett, Matthew. (2025). Il-15/il-15ra heterodimeric fc fusion proteins and uses thereof (U.S. Patent No. 12239688). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12239688

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