The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

May. 08, 2020
Applicants:

Industry-academic Cooperation Foundation Gyeongsang National University, Jinju-si, KR;

Stemcentric Co., Ltd., Anyang-si, KR;

Inventors:

Gyu Jin Rho, Jinju si, KR;

Kyung Min Kim, Seoul, KR;

Si Jung Jang, Jinji si, KR;

Sung Lim Lee, Jinju si, KR;

Bong Wook Park, Jinju si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2015.01); A61K 35/28 (2015.01); A61K 35/32 (2015.01); A61P 5/24 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 35/32 (2013.01); A61P 5/24 (2018.01);
Abstract

The present invention relates to a pharmaceutical composition including vitrified periodontal tissue-derived mesenchymal stem cells for prevention or treatment of male infertility. The pharmaceutical composition for prevention or treatment of male infertility according to the present invention recovers sex hormone levels in seminiferous tubules of atrophic testes and blood to normal levels through improvement in the activity of lipid metabolism enzymes in the liver, thereby exhibiting remarkable prophylactic and therapeutic effects on male infertility. In addition, the periodontal tissue-derived mesenchymal stem cells which are an active ingredient in the present invention can be obtained in the most non-invasive manner and as such, are expected to be advantageously used as a cell therapy product for male infertility.


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