The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Aug. 02, 2022
Zhejiang University, Hangzhou, CN;
Yang Zhu, Hangzhou, CN;
Yuwen Lu, Hangzhou, CN;
Changyou Gao, Hangzhou, CN;
Tanchen Ren, Hangzhou, CN;
Liyin Shen, Hangzhou, CN;
Xiaoqian Hong, Hangzhou, CN;
ZHEJIANG UNIVERSITY, Hangzhou, CN;
Abstract
A suture-free coagulation-assisted fixed cardiac patch and fabrication method thereof are provided. The cardiac patch includes a polymeric procoagulant base and a barbed microneedle fixed on the polymeric procoagulant base, and a side surface of the polymeric procoagulant base with the microneedle has a microporous structure which does not penetrate the solid base of the polymer; an included angle α between the microneedle and the plane where the polymeric procoagulant base located is 60-90°, and the microneedles are evenly distributed on the polymeric procoagulant base at a density of 5-50 threads/cm2; the barbs are located on the curved surface of the microneedle and are inclined toward the polymeric procoagulant base. The fabrication method includes using a mold pore-forming, a porogen pore-forming, or a thermally induced phase separation pore-forming, and combining the barbed microneedle while forming the microporous structure to obtain a suture-free coagulation-assisted fixed cardiac patch.