The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2025

Filed:

Jun. 29, 2023
Applicants:

California Institute of Technology, Pasadena, CA (US);

University of Southern California, Los Angeles, CA (US);

Inventors:

Yu-Chong Tai, Pasadena, CA (US);

Nicholas E. Scianmarello, Pasadena, CA (US);

Mark S. Humayun, Glendale, CA (US);

Assignees:

California Institute of Technology, Pasadena, CA (US);

University of Southern California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 3/10 (2006.01); A61B 5/00 (2006.01); A61B 10/00 (2006.01); G01F 22/00 (2006.01); G01G 19/00 (2006.01); G01N 1/10 (2006.01); G01N 30/02 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
A61B 3/101 (2013.01); A61B 5/6821 (2013.01); A61B 5/6867 (2013.01); A61B 10/0045 (2013.01); G01F 22/00 (2013.01); G01G 19/00 (2013.01); G01N 1/10 (2013.01); G01N 30/02 (2013.01); G01N 33/4875 (2013.01); A61B 2010/0067 (2013.01); G01N 2030/027 (2013.01);
Abstract

A lacrimal tear flow measurement device, and methods of manufacture and use, are described that includes a polymer microcapillary tube or similar structure having at least one end coated on the outside with soft silicone rubber and one end treated on the inside to be hydrophobic. The hydrophobic end keeps liquid from escaping or entering that end while allowing air to pass. The rest of the tube's insides may be hydrophilic or a neutral hydrophobe. As a Schirmer's test strip replacement, the entrance end of the device can be touched to the lacrimal lake of a patient's eye to collect suck up, or merely collect, tear fluid within the collection tube for weighing, volume measurement, or other analysis. Long-term collection devices for wear between doctors' visits can have a bypass channel allowing liquid to flow back onto the eye.


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