The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Jun. 11, 2020
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Jess Dreher Reed, Verona, WI (US);

Christian Gerald Krueger, Cambridge, WI (US);

Emilia Alfaro-Viquez, Madison, WI (US);

Sergio Madrigal-Carballo, Madison, WI (US);

Hilary Urena Saborio, Madison, WI (US);

Sundaram Gunasekaran, Madison, WI (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
D01F 8/18 (2006.01); C08G 73/02 (2006.01); C08K 11/00 (2006.01); D01F 8/14 (2006.01); D04H 13/00 (2006.01); C12Q 1/18 (2006.01);
U.S. Cl.
CPC ...
D01F 8/18 (2013.01); C08G 73/0266 (2013.01); C08K 11/00 (2013.01); D01F 8/14 (2013.01); D04H 13/00 (2013.01); C12Q 1/18 (2013.01); D10B 2505/04 (2013.01); D10B 2509/00 (2013.01);
Abstract

Composite nanofibers comprising polymers and tannins, methods of making same, and methods of use. The nanofibers include a polymer, such as a synthetic polymer, and a tannin. The tannin can include condensed tannins (proanthocyanidins) and/or hydrolyzable tannins. The nanofibers exhibit a number of structural and functional characteristics, such as enhanced swelling in aqueous liquid, enhanced antibacterial activity, enhanced bacterial adsorption, enhanced fibroblast adhesion, enhanced fibroblast proliferation, and enhanced surface coating of silver nanoparticles, among others. The nanofibers can be made by electrospinning a solvent mixture comprising the synthetic polymer and the tannin in a solvent. The nanofibers can be used in methods of isolating cells, methods of filtration, and methods of detecting cells, among others.


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