The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Nov. 19, 2019
Applicant:

University of Washington, Seattle, WA (US);

Inventors:

Alfredo Quijano Rubio, Seattle, WA (US);

Daniel Adriano Silva Manzano, Seattle, WA (US);

David Baker, Seattle, WA (US);

Umut Ulge, Seattle, WA (US);

Marc Joseph Lajoie, Seattle, WA (US);

Assignee:

UNIVERSITY OF WASHINGTON, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); A61K 38/20 (2006.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); C07K 14/54 (2006.01); C07K 14/55 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C40B 40/10 (2013.01); A61K 38/2013 (2013.01); A61K 38/2026 (2013.01); A61K 38/2086 (2013.01); A61P 35/00 (2018.01); A61P 37/04 (2018.01); C07K 14/5406 (2013.01); C07K 14/5443 (2013.01); C07K 14/55 (2013.01); A61K 48/00 (2013.01); C07K 2319/30 (2013.01);
Abstract

Conditionally active receptor agonists that, when activated, bind to IL-2 receptor βheterodimer (IL-2Rβ), IL-4 receptor αheterodimer (IL-4Rα), or IL-13 receptor a subunit (IL˜13 Rα) are disclosed, as are components of the conditionally active receptor agonists and methods for using the conditionally active receptor agonists.


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