The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Feb. 02, 2021
Natera, Inc., San Carlos, CA (US);
Solomon Moshkevich, Menlo Park, CA (US);
Bernhard Zimmermann, Manteca, CA (US);
Tudor Pompiliu Constantin, Berkley, CA (US);
Huseyin Eser Kirkizlar, Los Angeles, CA (US);
Allison Ryan, Belmont, CA (US);
Styrmir Sigurjonsson, San Jose, CA (US);
Felipe Acosta Archila, Foster City, CA (US);
Ryan Swenerton, Millbrae, CA (US);
Natera, Inc., San Carlos, CA (US);
Abstract
The present disclosure provides methods for determining the status of an allograft within a transplant recipient from genotypic data measured from a mixed sample of DNA comprising DNA from both the transplant recipient and from the donor. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.