The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Dec. 19, 2019
Applicant:

Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, CN;

Inventors:

Yinxiong Li, Guangzhou, CN;

Tingcai Pan, Guangzhou, CN;

Yan Chen, Guangzhou, CN;

Yuanqi Zhuang, Guangzhou, CN;

Fan Yang, Guangzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/067 (2013.01); C12N 2500/25 (2013.01); C12N 2501/11 (2013.01); C12N 2501/12 (2013.01); C12N 2501/15 (2013.01); C12N 2501/155 (2013.01); C12N 2501/41 (2013.01); C12N 2501/73 (2013.01);
Abstract

Provided are a culture medium for expanding and cultivating human liver progenitor cells and an application thereof. The chemical components of the formula of the described culture medium are clear, no serum is present, and various components thereof cooperate with each other to synergize. The culture medium is used for the long-term expansion and cultivation of liver progenitor cells in vitro and is used for maintaining the dryness thereof, is beneficial in quickly and efficiently obtaining a large number of functional liver cells, and is suitable for clinical hepatocyte transplantation application as well as for the use of hepatocyte reactors in bioartificial livers.


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