The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Jul. 11, 2022
Applicant:

Precigen, Inc., Germantown, MD (US);

Inventors:

Jeffrey David Orth, Germantown, MD (US);

Louis A. Clark, Germantown, MD (US);

Lily Yuin Chao, Germantown, MD (US);

Na My Trinh, Germantown, MD (US);

Christopher Cheyney Farwell, Germantown, MD (US);

Xinhua Zhao, Germantown, MD (US);

Matthias Helmut Schmalisch, Germantown, MD (US);

Grayson Thomas Wawrzyn, Germantown, MD (US);

Xuezhi Li, Germantown, MD (US);

Mark Anton Held, Germantown, MD (US);

Kevin Lee Dietzel, Germantown, MD (US);

James Kealey, Germantown, MD (US);

Assignee:

PRECIGEN, INC., Germantown, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12N 9/12 (2006.01); C12N 9/88 (2006.01); C12N 15/52 (2006.01); C12N 15/70 (2006.01); C12P 7/00 (2006.01); C12P 7/16 (2006.01); C12P 7/24 (2006.01);
U.S. Cl.
CPC ...
C12N 15/52 (2013.01); C12N 9/0006 (2013.01); C12N 9/1022 (2013.01); C12N 9/1205 (2013.01); C12N 9/88 (2013.01); C12N 15/70 (2013.01); C12P 7/16 (2013.01); C12P 7/24 (2013.01); C12Y 101/01001 (2013.01); C12Y 101/01086 (2013.01); C12Y 202/01006 (2013.01); C12Y 401/01072 (2013.01); C12Y 402/01009 (2013.01);
Abstract

Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as isobutanol are disclosed. For example, genetically modified methanotrophs that are capable of generating isobutanol at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed.


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