The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Jun. 25, 2020
Aerosol Dynamics Inc., Berkeley, CA (US);
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Arantzazu Eiguren Fernandez, Richmond, CA (US);
Gregory Stephen Lewis, Berkeley, CA (US);
Steven Russel Spielman, Oakland, CA (US);
Chang-Yu Wu, Gainesville, FL (US);
Trevor Benson Tilly, Columbus, OH (US);
Aerosol Dynamics Inc., Berkeley, CA (US);
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Abstract
An apparatus and method for the delivery and deposition of particles air-liquid-interface (ALI) cell cultures includes a sample inlet coupled to a growth tube having interior walls that are wet. The growth tube is configured to operate at a first temperature along a first length of the tube and a second temperature along a second length positioned between the first length and a growth tube outlet. The apparatus also includes a nozzle plate having a plurality of nozzles. The exposure chamber adapted to hold cell cultures at an air-liquid interface positioned underneath the plurality of nozzles and a temperature regulator adapted to control a temperature of the exposure chamber. The apparatus also includes a controller including instructions operable to cause the controller to maintain a relative humidity within the exposure chamber by controlling at least the second temperature of the growth tube and the temperature of the exposure chamber.