The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Mar. 30, 2022
Applicant:

Ferring B.v., Hoofddorp, NL;

Inventors:

Ian Cottingham, St. Prex, CH;

Daniel Plaksin, St. Prex, CH;

Richard White, San Diego, CA (US);

Assignee:

Ferring B.V., Hoofddorp, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/575 (2006.01); A61K 38/16 (2006.01); C07K 14/59 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/575 (2013.01); C07K 14/59 (2013.01); C12P 21/005 (2013.01); A61K 38/16 (2013.01);
Abstract

Described are pharmaceutical compositions comprising recombinant human chorionic gonadotropin (hCG) and optionally follicle stimulating hormone (FSH), wherein the recombinant hCG in the composition comprises α2,3- and α2,6-sialylation and comprises mono-(1S), di-(2S), tri-(3S) and tetra-(4S) sialylated glycan structures. The recombinant hCG may be obtained by expression in a human cell line, such as the PER.C6 cell line, optionally wherein the cell line is modified using α2,3-sialyltransferase.


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