The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2025
Filed:
Mar. 08, 2023
Applicant:
Yale University, New Haven, CT (US);
Inventors:
David Caianiello, New Haven, CT (US);
Edward DeRamon, New Haven, CT (US);
David Spiegel, New Haven, CT (US);
Assignee:
YALE UNIVERSITY, New Haven, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/18 (2006.01); A61P 9/00 (2006.01); C07D 225/08 (2006.01);
U.S. Cl.
CPC ...
C07H 15/18 (2013.01); A61P 9/00 (2018.01); C07D 225/08 (2013.01);
Abstract
The disclosure describes compounds of Formula Ia, which in non-limiting aspects contain an asialoglycoprotein receptor (ASGPR) binding moiety and an anti-βAR binding moiety. Compounds of Formula Ia are useful in preventing, treating, and/or ameliorating heart failure in a subject when administered in therapeutically effective amounts.