The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Jan. 15, 2021
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Christopher McBride, South San Francisco, CA (US);

Lynnie Lin Trzoss, South San Francisco, CA (US);

Amogh Boloor, South San Francisco, CA (US);

Nadezda V. Sokolova, South San Francisco, CA (US);

Richard M. Pastor, South San Francisco, CA (US);

Steven Thomas Staben, South San Francisco, CA (US);

Craig Stivala, South San Francisco, CA (US);

Matthew Volgraf, South San Francisco, CA (US);

Sarah M. Bronner, South San Francisco, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 31/14 (2006.01); A61P 31/16 (2006.01); A61P 31/18 (2006.01); C07D 231/18 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61P 31/04 (2018.01); A61P 31/12 (2018.01); A61P 31/14 (2018.01); A61P 31/16 (2018.01); A61P 31/18 (2018.01); C07D 231/18 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The present disclosure relates to novel sulfonimidamide compounds and related compounds and their use in treating a disorder responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.


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