The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 25, 2025

Filed:

Sep. 23, 2019
Applicant:

Shanghai Ennovabio Pharmaceuticals Co., Ltd., Shanghai, CN;

Inventors:

Lei Jiang, Shanghai, CN;

Jianwen Deng, Shanghai, CN;

Zhiyong Feng, Shanghai, CN;

Shengyang Liu, Shanghai, CN;

Xudong Mao, Shanghai, CN;

Ke Shang, Shanghai, CN;

Jianyong Shou, Shanghai, CN;

Danyi Wu, Shanghai, CN;

Xiaoping Xie, Shanghai, CN;

Yuan Xu, Shanghai, CN;

Haixia Zhao, Shanghai, CN;

Jianhua Zhang, Shanghai, CN;

Mingwei Zheng, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.


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